7-Hydroxymitragynine (7-OH) is a psychoactive component of kratom — and it’s showing up in increasingly in new concentrate and synthetic forms in products found in gas stations and convenience stores. These newer formulations have increased concerns among researchers, clinicians, and advocates about misuse, unpredictable potency, and emerging health risks. Even though kratom is widely available, there’s still limited public understanding of how synthetic and concentrated 7-OH