Jean Lud Cadet, M.D. came to NYC from Haiti in 1970. He attended Columbia University College of Physicians and Surgeons from which he obtained his MD in 1979. He did residency training in Psychiatry at the Department of Psychiatry at Columbia University and in Neurology at the Department of Neurology at Mount Sinai Medical Center, both in New York City. He came to NIDA, IRP in 1992 where he is presently a senior NIH investigator and the Chief of the Molecular Neuropsychiatry Research Branch. Dr. Cadet has co-authored more than 300 papers, abstracts and book chapters on the molecular neurobiology of addiction and neurodegeneration. He has also written about cognitive deficits in cocaine and marijuana abusers. Presently, his laboratory studies the molecular mechanisms of stimulant-induced changes in the expression of genes and proteins in specific neuronal cells. He is also investigating the epigenetic bases of methamphetamine and oxycodone addiction.