Methamphetamine , a well-known psychostimulant drugs of abuse is in a resurgence in people using opioids and others. While many treatment options exist for patients with opioid use disorders, alcohol use disorders, and even tobacco smokers, there are far fewer options for people trying to stop using methamphetamines. No known medical treatments exist for overdose, dependence, craving, relapse, or to reverse all of the effects of methamphetamine binges and dependence. Experts studying substance use disorders recognize that their effects from misuse, especially the misuse of methamphetamine, can linger even after periods of abstinence.Patients treated for methamphetamine binges, or dependence, for example, often suffer from cognitive impairments, including psychosis. Some of the persistent problems may reflect underlying brain change or even damage. If overlooked, cognitive problems can limit the effectiveness of treatment. They can also create a dangerous hopelessness or relapse cycle. That’s one reason why it’s so important to understand how substances like methamphetamine may alter the brain’s structure.
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It is important to understand how substances, including prescribed medications, can interact with each other and other substances. Mixing medications-- whether the medication is prescribed by a doctor, available over-the-counter, or otherwise-- can be dangerous both in the long and the short-term. Make sure to consult with your prescribing doctor when you have any questions about what medications you are taking and how they may interact with other substances you may be using. It is also important to know what your medications are being prescribed to treat, and to be honest when your doctor ask what medications or supplements you are taking so they can better understand what may interact negatively with each other.
It is important to note that mixing 2 or more substances significantly increases the risk of dangerous or fatal effects. For example, a study done in Florida found that over 90% of opioid overdose deaths in the state included other, non-opioid drugs with an average of 2–3 drugs other than the opioids found at autopsy. (1)